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Beilstein J. Org. Chem. 2022, 18, 631–638, doi:10.3762/bjoc.18.63
Graphical Abstract
Figure 1: Biologically active cholic acid hybridized with different heterocyclic scaffolds.
Scheme 1: Synthesis of cholyl 1,3,4-oxadiazole-2-thiol 2.
Scheme 2: Synthesis of cholyl 2-(propargylthio)-1,3,4-oxadiazole 3.
Scheme 3: Synthesis of target compounds 4a–v.
Figure 2: Structures of target compounds 4a–v.